Red cell distribution width (RDW) is a hematological parameter that indicates the variability in red blood cell volume, and an elevated RDW level reflects the body’s inflammatory state.[12] Previous studies have demonstrated the correlation of RDW with predicting stroke-related mortality and poor clinical outcomes.[13–15] During the inflammatory cascade after stroke, cytokines such as interleukin-6 and tumor necrosis factor-α are released. This evidence concerns the gene TNF and Stroke.