Mettl3, a target of miR-590-5p, demonstrates a negative correlation with miR-590-5p and consequently promotes tumor progression.[104] In addition, it was found that lncRNAs, such as LINC01559, may act as molecular sponges of miR-106b-5p, regulating the expression of PTEN through miR-106b-5p, and the whole axis plays a role in tumor suppression. This evidence concerns the gene PTEN and neoplasm.