METTL3 and cancer: Linc-UROD contributes to glycolysis and the malignant phenotype of PC cells by stabilizing the glycolytic enzymes enolase 1 and pyruvate kinase muscle isozyme.[75] Leukemia inhibitory factor receptor antisense RNA 1 (LIFR-AS1) is a novel cancer-associated lncRNA, transcribed from the LIFR gene in an antisense manner, and Mettl3 was shown to induce LIFR-AS1 m6A to enhance its mRNA stability.