However, as endorsed by a recent Clinical Consensus by the European Society of Cardiology (ESC), the accurate use and interpretation of NT-proBNP cut-offs—after careful adjustment for key confounders such as age, body mass index (BMI), estimated glomerular filtration rate (eGFR), and atrial fibrillation (AF)—can also be regarded as a tool for the stratification of patients in terms of HF risk. Here, NPPB is linked to atrial fibrillation.