We also found a relationship between initial plasma endothelin 1 concentrations and serum albumin concentrations following 1 year (n = 27; p = 0.05; r = −0.4) (Figure 27) and 2 years (n = 27; p = 0.05; r = −0.4) (Figure 28) of monitoring in the chronic kidney disease cohort. The gene discussed is EDN1; the disease is chronic kidney disease.