In terms of diagnosing mTBI and sTBI, the authors were able to identify sTBI patients with 100% sensitivity and specificity (area under the curve (AUC) = 1) using IL-6, while for mTBI, they observed that the ratio of IL-6/IL-8 had the best results (AUC = 0.829). Here, CXCL8 is linked to concussion.