In our study, the association between high CONUT scores and mortality may be explained by the fact that the components of the CONUT score (albumin, total cholesterol, and lymphocyte count) reflect key pathophysiological disturbances commonly observed in palliative care patients—such as malnutrition, inflammation, and immune dysfunction—which are known to be significant predictors of prognosis [2,10]. This evidence concerns the gene ALB and immune system disorder.