CXCL8 and chronic kidney disease: H. Lu et al., J. Mahendra et al., and M. Mazurek-Mochol, in their studies, confirmed a relationship between the levels of IL-8, TNF-α, VEGF, and periodontopathogenic bacteria, thereby demonstrating the role of inflammatory biomarkers in periodontal diseases and systemic inflammation contribution in CKD [48,53,54].