In multivariable Cox regression analysis, tumor differentiation grade (adjusted HR: 3.985, 95% CI: 1.457–10.898, p = 0.007) and pretreatment CEA levels (adjusted HR: 2.416, 95% CI: 1.161–5.026, p = 0.018) emerged as independent prognostic determinants. Here, CEACAM5 is linked to neoplasm.