For the purpose of this review, we focused on the existing evidence of some of most relevant cytokines released into the blood upon infection of these three categories: antiviral (IFNγ, CXCL1, CXCL10 also called IP-10), inflammatory (IL-1β, IL-6, IL-10, IL-2, IL-4, IL-7, IL-8, and TNFα), and monocyte chemoattractant proteins (MCP1, also called CCL2, and MCP3, also called CCL7), as well as MIP-1α, also called CCL3, GM-CSF, and GSCF [7,15,61,62]. The gene discussed is IL6; the disease is infection.