Examples of these inhibitors include anti-tumour drugs such as prinomastat, which inhibits various MMPs, such as MMP-1, -2, -3, -7, -9, and -14; ilomastat, which inhibits various MMPs, including MMP-2 and -9; marimastat, which inhibits MMP-1, -2, -3, -7, -9, and -12; tanomastat, which inhibits MMP-2, -3, -9, and -13; metastat, which inhibits MMP-1, -2, -8, -9, and -13; and D2163, which inhibits MMP-1, -2, and -9 [213,215,216]. This evidence concerns the gene MMP2 and neoplasm.