Certain circRNAs identified in our analysis demonstrated exceptionally strong discriminatory power across breast cancer subtypes, e.g., hsa_circRNA_104310 (host gene: ZDHHC4), hsa_circRNA_404935 (ZBTB16), hsa_circRNA_003641 (ATM), and hsa_circRNA_102445 (CARM1) (Figure 4A,B, Supplementary Table S3). This evidence concerns the gene CARM1 and breast carcinoma.