Furthermore, while an earlier HLA class II typing study in an Indian population reported that the absence of HLA-DQA1*01:02 and the presence of HLA-DQB1*02:01 increased the risk of anti-TB DILI, Nicoletti et al. found elevated frequencies of HLA-DQA1*01:03 and HLA-DQA1*03:01 in their cohort—though these associations were not replicated in European patients, indicating possible ethnic or drug-specific variability in genetic susceptibility [40]. This evidence concerns the gene HLA-DQB1 and tuberculosis.