However, although there are several studies on the cellular targets of benzoxaborole, such as phosphodiesterase 4 (PDE4) [8], leucyl-tRNA synthetases (LeuRS) [9] and cleavage and polyadenylation specificity factor 3 (CPSF3) [10], the definitive target(s) of our anti-cancer compounds remains elusive and calls for more in-depth investigation. Here, CPSF3 is linked to cancer.