We believe that the most optimal option for standardizing the assessment of changes in the biological properties of a tumor depending on the nutrient medium, the introduction of growth factors, chemical, physical, or biological effects, and the possible response to chemotherapy, in addition to the visual assessment of the PI curve, will be the EVOC score, calculated as the ratio of the Ki-67 AUC of the control sample to the Ki-67 AUC of the experimental sample taken from the primary tumor. The gene discussed is MKI67; the disease is neoplasm.