Similarly, intersection of the 42 candidate sex-related hub genes with DEGs from the OFM vs. OM and NOFM vs. NOM comparisons resulted in 9 co-hub genes: LRRC2 (Leucine rich repeat containing 2), LOC106038083, LOC125179635, UBE2R2 (Ubiquitin conjugating enzyme E2 R2), LOC106048542, LOC136788421, LOC136789444, SLC1A1 (Solute carrier family 1), and LOC106048358 (Figure 3D). The gene discussed is UBE2R2; the disease is ocular melanoma.