Moreover, analyses of gene expression and DNA copy number showed that CCT2, CCT3, CCT5, CCT6A, and CCT7 are upregulated in GBM compared with normal brain tissue, while CCT2, CCT3, CCT5, CCT6A, and CCT8 display higher copy numbers than in low-grade gliomas [29]. The gene discussed is CCT5; the disease is central nervous system cancer.