While the involvement of the CCT complex in the main GBM pathways, such as Wnt, TGF-β, VEGF, EGFR, CDKN2A, NF-κB, and the PI3K/AKT/mTOR, is under continuous observation and investigation by researchers [28,29,30], its role in the cascade belonging to GBM metabolic processes is less explored. The gene discussed is CDKN2A; the disease is glioblastoma.