-subunit SDHB knockdown increases OC cell proliferation and endothelial to mesenchymal transition in vitro [180]-subunit SDHB knockdown results in mitochondrial dysfunction in OC in vitro [180]-shikonin induces cell death in SDHA overexpressing OC cells in vitro [140]-ONC201 inhibits tumor growth and decreases VEGF expression in vivo [174]. This evidence concerns the gene SDHB and neoplasm.