NTRK1 is located at 1q23.1, and an increased copy number involving that site is considered a potential oncogenic alteration in patients with malignant melanoma and hepatocellular carcinoma, but gene amplification including 1q23.1 is not a common structural variant in esophageal or gastric cancers [24,25]. The gene discussed is NTRK1; the disease is hepatocellular carcinoma.