APOA1 and early-onset autosomal dominant Alzheimer disease: In this article, we highlight the cross-interactions of amyloid with the studied apolipoprotein genes, which are presented as an integrated part of the amyloid neurotoxicity process, or conversely, as a preventive role in the pathogenesis of Alzheimer’s disease and post-ischemic brain neurodegeneration, especially through the direct binding of apolipoprotein A1 to amyloid [61].