Specifically, the use of photoconvertible immune cell reporters (e.g., Kaede or KikGR mice) and longitudinal in vivo imaging could be employed to definitively demonstrate the sequestration of CXCR3+ effector cells in the lungs or circulation in response to tumor-driven CXCL10 gradients [206,207]. This evidence concerns the gene CXCL10 and neoplasm.