Also, this group presented leukocytosis (p= 0.044), neutrophilia (p = 0.003), higher CK levels (p = 0.005), and had C3 (p = 0.07) and C4 (p = 0.046) hypocomplementemia in comparison to DM patients without TMA (Table 1). This evidence concerns the gene C3 and Increased total leukocyte count.