FKBP5 and chronic obstructive pulmonary disease: Moreover, there has been reports indicating that FKBP5 up-regulation is accociated with worse asthma control in the population of obese children [34], while in a COPD context the single nucleotide polymorphism of this gene (rs4713916) was found to be associated with higher quality of life in COPD patients [35], and functional outcomes [36], indicating the relevance of this gene both in the broader context of respiratory diseases as well as COPD.