Another recent study conducted by Adewale et al. demonstrates that the ethanolic extract of Moringa oleifera leaves exhibits an immunomodulatory effect by triggering programmed cell death pathway (apoptosis) in Jurkat cancer cells through up-regulation of CCR7, especially when those cancer cells were stimulated with CD3 and CD54 or CD28 [145]. This evidence concerns the gene ICAM1 and cancer.