The hub genes KIF4A, NUSAP1, BUB1B, CEP55, DLGAP5, NCAPG, CDK1, MELK, KIF11, and KIF20A converge on pathways that are essential for mitosis, spindle formation, and cell-cycle progression, all of which are recognized hallmarks of cancer development. This evidence concerns the gene NUSAP1 and cancer.