Notably, CDN shares the “low toxicity + multi-target regulation” advantage of other food-derived anti-fibrotic compounds: Resveratrol (abundant in grapes and peanuts) mitigates BLM-induced pulmonary fibrosis in mice by regulating the SIRT1/AMPK metabolic axis [30], while curcumin (the active component of turmeric) alleviates IPF by modulating gut–lung axis metabolism [31]. Here, SIRT1 is linked to idiopathic pulmonary fibrosis.