Figure 3E showed that has-miR-222-3p negatively correlated with TMBIM6 in PRAD (Figure 3E). We have also researched the expression level of has-miR-222-3p in PRAD and found that in the normal group has-miR-222-3p was significantly highly expressed (Figure 3F). Overall survival analysis showed the high expression group of hsa-miR-222-3p has better survival in PRAD (Figure 3G,H). This evidence concerns the gene TMBIM6 and prostate adenocarcinoma.