Among Rajput caste, seven RGDs were caste-specific including Cerebrotendinous Xanthomatosis, congenital diarrheal syndrome, HSD17B4-related disorder, hypercholesterolemia type B, Menke-Hennekam Syndrome, RAG1-associated disorder and Sjögren-Larsson Syndrome. The gene discussed is HSD17B4; the disease is cerebrotendinous xanthomatosis.