Regarding the NIS linear T-cell epitopes, our analysis revealed that the peptide NLMDFNPDPRSRYTF was the one with the highest binding affinity (percentile rank 0.01–0.03) for the HLA-DRB1*03:05, HLA-DRB1*03:14 and HLA-DRB1*03:40 alleles, which, according to the literature, are those most associated with the risk of developing SS and HT in the Spanish population [14,50,51]. The gene discussed is HLA-DRB1; the disease is hematocrit.