Familial FTD is present in approximately 25–50% with autosomal-dominant inheritance showing mutations in MAPT, GRN, chromosome 9 open reading frame 72 (C9orf72), valosin-containing protein (VCP), and charged multivesicular body protein 2B (CHMP2B) [111]. This evidence concerns the gene C9orf72 and frontotemporal dementia.