However, B2M levels were positively associated with galectin-9 levels (β = 0.65, p = 0.012) in patients with CLL (Figure 2).The Rai stage showed no statistically significant association with sCD25 levels (β = −901.67, p = 0.274), TIM-3 levels (β = −2521.88, p = 0.078), galectin-9 levels (β = 218.93, p = 0.099), PD-1 (β = 56.00, p = 0.537) levels, or PD-L1 levels (β = 2.21, p = 0.843) (Supplementary Table S2). This evidence concerns the gene PDCD1 and B-cell chronic lymphocytic leukemia.