Comparative context with other m6A regulators: in respiratory diseases, ALKBH5 and FTO oppose METTL3 by erasing m6A marks, frequently shaping metabolic adaptation and stress responses; YTH proteins (YTHDF1/2/3, YTHDC1/2) and IGF2BPs determine the fate of m6A-tagged transcripts (translation, decay and stabilization). This evidence concerns the gene METTL3 and respiratory system disorder.