KEGG pathway analyses revealed enrichment in neuroactive ligand-receptor interaction pathways, classical signaling pathways (e.g., PI3K-Akt, TNF, IL-17), tumor-associated pathways (e.g., prostate cancer, small cell lung cancer, bladder cancer), and metabolic and structural pathways (e.g., lipid and atherosclerosis, proteoglycans, proteasome, and calcium signaling pathways), as well as pathways related to viral infections (e.g., Epstein–Barr virus, human papillomavirus, human cytomegalovirus), immune responses (e.g., phagosome, lysosome), and cell death (e.g., apoptosis). The gene discussed is TNF; the disease is urinary bladder carcinoma.