Its role in the development of heart failure and myocardial remodelling is at present unknown, although at least one of the three receptors involved in chemerin cell signalling, C-C chemokine receptor-like 2 (CCRL2), has been identified in the heart and shown to participate in experimental autoimmune myocarditis in mice [198]. This evidence concerns the gene CCRL2 and autoimmune myocarditis.