A 27-year-old Caucasian (Bulgarian) female (body mass index/BMI/25.7 kg/m2) consulted with an endocrinologist because of PCOS, diagnosed in adolescence based on hirsutism, menstrual disturbances, increased androgens, and luteinizing hormone (LH) levels (14.5 IU/L), as well as an ultrasound finding of polycystic ovaries. This evidence concerns the gene PLOD1 and Hirsutism.