SLC9C1 and neoplasm: The Warburg effect, describing tumor cells’ increased aerobic glycolysis, drives lactate and proton (H+) overproduction; these acids are extruded via a Na+/H+ exchanger (NHE), the H+-lactate co-transporter, monocarboxylate transporters (MCTs), and the H+-ATPase (H+ pump), which lead to the secretion of H+ creating an acidic tumor microenvironment and an alkaline cytosolic environment [33,34].