TYR and melanoma: In cellular models (SK-Mel-28 melanoma cells), phycocyanin demonstrated tyrosinase inhibition potential after 60 min/120 min–30.88 μg/mL/39.87 μg/mL, respectively, a result comparable to the ascorbic acid control (34.06 μg/mL/17.48 μg/mL) [30].