Allergic Asthma (AA) is characterized by elevated levels of IgE; type 2 cytokines, including interleukin-4 (IL-4) and IL-13; Th17 cytokines, such as interleukin-17A-F, IL-21, and IL-22; mucus hypersecretion; eosinophilia; and airway hyperresponsiveness (AHR) [1,2]. The gene discussed is IL4; the disease is airway hyperresponsiveness.