FASN and hepatocellular carcinoma: In a mouse model of HCC, treatment with curcumin significantly decreased the levels of metabolic markers, including lactate dehydrogenase (LDH), triglycerides (TG), and FASN in serum, while upregulating the mRNA expression of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A1 (ApoA1).