Results demonstrated that the NASH group had significantly increased mRNA expression levels of oxidative stress-related markers, including Hmox1, Cybb, Ncf1, and NAD(P)H dehydrogenase quinone 1 (Nqo1) (12.46 ± 0.53-fold for Hmox1, 15.55 ± 1.10-fold for Cybb, 18.88 ± 1.01-fold for Ncf1, 3.71 ± 0.39-fold for Nqo1; all p < 0.001 versus control). Here, HMOX1 is linked to metabolic dysfunction-associated steatohepatitis.