At the highest concentration, APE 100 significantly reduced expression levels (1.98 ± 0.54 for Acta2; 26.21 ± 10.43 for Col1a1; 2.19 ± 0.16 for Des; 3.31 ± 0.34 for Tgfb1; all p < 0.001 versus the NASH group; Figure 12a–d). The gene discussed is ACTA2; the disease is metabolic dysfunction-associated steatohepatitis.