TP53 and neoplasm: TP53 alterations, namely a copy number loss with CN = 0.19 in OS#1 and two missense variants (R273H in OS#2 A, and V216M in both OS#5 A and OS#5 B, two metastatic samples deriving from the same patient), were found only in OS patients (3 out of 7 patients, 43%), and not in other tumor histotypes.