As illustrated in Figure 3A,B, the percentage of CD45+ cells in live cells across both tumour and peritumour tissues, as well as their respective ALI organoids, ranged from 0.5% to 56.8%, showing substantial inter-tumoural heterogeneity, with no significant differences observed between the original tissues and matched organoids (Figure 3B). Here, PTPRC is linked to neoplasm.