Multiple lines of transcriptomic evidence in tumor-educated THP1 cells point to STAT3 pathway activation, including upregulation of canonical STAT3 targets (SOCS3, CISH, BCL3, JUNB, PIM1) and increased expression of STAT3-activating ligands (IL6, IL11, LIF, OSM) in response to TNBC contact. This evidence concerns the gene SOCS3 and neoplasm.