SNAI1 and neoplasm: Numerous reviews and experimental studies have demonstrated that FGF/FGFR signaling can initiate or potentiate EMT-related molecular programs, typically accompanied by altered expression of EMT-associated transcription factors (such as Snail, Slug, and Twist) and epithelial markers (such as E-cadherin), thereby promoting mesenchymal phenotypes and stem-like properties in tumor cells [130,160].