CD44 and neoplasm: A significantly higher uptake in SKOV3 ovarian cancer cells and a 4.82-fold higher tumour accumulation in vivo than single ligand control, as shown in Figure 4, was exhibited by dual CD44 and folate receptor-targeted hyaluronic acid-ceramide folic acid nanoparticles, showing synergistic targeting and improved visualisation of intraperitoneal tumours [107].