Briefly, the Janus kinase (JAK)/signal transducer and activator of transcription (STAT)/phosphatidylinositol-3 kinase(PI3k)/protein kinase B (AkT)/mammalian target of rapamycin (mTOR) signaling pathways are overreactive in BC, driving tumor cells’ survival and proliferation [128,129]. The gene discussed is AKT1; the disease is breast cancer.