This finding is consistent with previous studies, such as those by Hu et al., who demonstrated that FGF1 improves lipid metabolism by promoting AMPK phosphorylation [23], and studies showing that a non-mitogenic variant of FGF1 can prevent and reverse liver steatosis and steatohepatitis by activating AMPK [15]. Here, FGF1 is linked to Hepatic steatosis.