This result is consistent with the abnormal expression characteristics of TREM1 in cardiovascular diseases such as atherosclerosis and atrial fibrillation reported in previous studies [26,27], suggesting that TREM1 may act as a key regulatory molecule in the pathological process of MIRI, participating in the inflammatory cascade reaction and cell death regulation after myocardial ischemia-reperfusion. This evidence concerns the gene TREM1 and atherosclerosis.