Fourteen of these participants had the APOB c.10238del (NM_000384.2) or APOB c.7537C>T (NM_000384.2) variant, which are associated with familial hypobetalipoproteinemia, a rare monogenic condition characterized by low LDL-C levels, distinct from FH. The gene discussed is APOB; the disease is familial hyperaldosteronism.