A study by Elliot et al. found that compared with genetic ancestry-matchedCKD patients with low-risk APOL1 genotypes, high-risk APOL1 genotypepatients were at higher risk of kidney failure (hazard ratio [HR]=1.58),higher eGFR decline (6.55 vs 3.63 mL/min/1.73 m2/yr), and wereyounger at kidney failure (45.1 vs 53.6 years), with the G1/G1 genotype athighest risk. Here, APOL1 is linked to kidney failure.