In contrast, the CGA vs. AGA comparison revealed enrichment across 21 pathways (Figure 4B, Table S2), including prostate cancer (protein p = 2.92 × 10−2; metabolite p = 3.97 × 10−5) and thyroid hormone signaling (protein p = 1.71 × 10−2; metabolite p = 3.47 × 10−2), which exhibited dysregulation at both molecular levels. The gene discussed is TG; the disease is Familial prostate cancer.